Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11539725 | 1.00 | NPSR1 (0.55) | NPSR1CTSLNPC1MAPTTP53 | |
| SCHEMBL11540675 | 0.85 | KDM4E (0.41) | NPSR1CTSLMAPTALDH1A1KDM4E | |
| SCHEMBL11540672 | 0.85 | KDM4E (0.41) | NPSR1CTSLMAPTALDH1A1KDM4E | |
| SCHEMBL11538757 | 0.84 | MAPT (0.49) | NPSR1CTSLNPC1MAPTTP53 | |
| SCHEMBL11538753 | 0.84 | MAPT (0.49) | NPSR1CTSLNPC1MAPTTP53 | |
| SCHEMBL11540587 | 0.82 | NOTUM (0.40) | NPSR1CTSLNPC1MAPTALDH1A1 | |
| SCHEMBL11539391 | 0.82 | NOTUM (0.40) | NPSR1CTSLNPC1MAPTALDH1A1 | |
| SCHEMBL13114090 | 0.74 | NPSR1 (0.58) | NPSR1CTSLNPC1MAPTTP53 | |
| SCHEMBL7878503 | 0.74 | CTSL (0.62) | NPSR1CTSLNPC1MAPTALDH1A1 | |
| SCHEMBL29991312 | 0.74 | CTSL (0.62) | NPSR1CTSLNPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169097-A | GASTRIC ANTISECRETORY AGENTS | MORTON-NORWICH PRODUCTS, INC. (US) | 1979-09-25 | — | — | US | claimed |
| US-4169097-A | GASTRIC ANTISECRETORY AGENTS | MORTON-NORWICH PRODUCTS, INC. (US) | 1979-09-25 | — | — | US | disclosed |