Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11539391 | 1.00 | NOTUM (0.40) | NOTUMALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL11540152 | 0.86 | LMNA (0.41) | NOTUMALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL11540155 | 0.86 | LMNA (0.41) | NOTUMALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL12609459 | 0.85 | NOTUM (0.43) | NOTUMALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL11540354 | 0.84 | MTNR1A (0.41) | NOTUMALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL11539890 | 0.83 | NOTUM (0.47) | NOTUMALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL11539893 | 0.83 | NOTUM (0.47) | NOTUMALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL11540672 | 0.82 | KDM4E (0.41) | NOTUMALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL11539728 | 0.82 | NPSR1 (0.55) | NOTUMALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL11540675 | 0.82 | KDM4E (0.41) | NOTUMALDH1A1SMN1; SMN2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169097-A | GASTRIC ANTISECRETORY AGENTS | MORTON-NORWICH PRODUCTS, INC. (US) | 1979-09-25 | — | — | US | claimed |