Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.40 |
| ▸ | RELA | Q04206 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543148 | 1.00 | MAPT (0.47) | MAPTKDM4ENPC1RAB9ANFKB1 | |
| SCHEMBL11538757 | 0.87 | MAPT (0.49) | MAPTKDM4ENPC1RAB9ANFKB1 | |
| SCHEMBL11538753 | 0.87 | MAPT (0.49) | MAPTKDM4ENPC1RAB9ANFKB1 | |
| SCHEMBL11540155 | 0.82 | LMNA (0.41) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL11540152 | 0.82 | LMNA (0.41) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL13351584 | 0.78 | ALDH1A1 (0.39) | MAPTKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL8027812 | 0.78 | KDM4E (0.43) | MAPTKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL20205940 | 0.77 | HPGD (0.48) | MAPTKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL11540786 | 0.75 | ALDH1A1 (0.46) | MAPTKDM4ENPC1RAB9ANFKB1 | |
| SCHEMBL11540789 | 0.75 | ALDH1A1 (0.46) | MAPTKDM4ENPC1RAB9ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169097-A | GASTRIC ANTISECRETORY AGENTS | MORTON-NORWICH PRODUCTS, INC. (US) | 1979-09-25 | — | — | US | claimed |