Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 3/20 | 0.49 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27417109 | 0.94 | LTA4H (0.51) | CA1CA2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL7416290 | 0.94 | CA1 (0.55) | CA1CA2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL7693841 | 0.93 | LTA4H (0.50) | CA1CA2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL8016082 | 0.91 | CA1 (0.56) | CA1CA2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL3928470 | 0.86 | ALDH1A1 (0.53) | CA1CA2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL1011973 | 0.85 | HTT (0.64) | CA1CA2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL5424654 | 0.85 | LTA4H (0.55) | CA1CA2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL17925349 | 0.84 | HTT (0.51) | CA1CA2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL7150639 | 0.84 | LTA4H (0.56) | CA1CA2ALDH1A1MAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL27650576 | 0.84 | LTA4H (0.54) | CA1CA2ALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167632-A | APPETITE SUPPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1979-09-11 | — | — | US | disclosed |
| US-4122265-A | APPETITE SUPPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1978-10-24 | — | — | US | disclosed |