Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8016082 | 0.97 | CA1 (0.56) | CA1CA2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL11538899 | 0.94 | CA1 (0.52) | CA1CA2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL27417109 | 0.91 | LTA4H (0.51) | CA1CA2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL7693841 | 0.90 | LTA4H (0.50) | CA1CA2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL7695939 | 0.86 | ALDH1A1 (0.66) | CA1CA2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL3928470 | 0.86 | ALDH1A1 (0.53) | CA1CA2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL17177605 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1LTA4HHTT | |
| SCHEMBL7703370 | 0.86 | CA1 (0.48) | CA1CA2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL2816305 | 0.85 | ALDH1A1 (0.56) | CA1CA2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL6676173 | 0.85 | ALDH1A1 (0.56) | CA1CA2ALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3130608-A1 | (ANTI-HER2 ANTIBODY)-DRUG CONJUGATE | Daiichi Sankyo Co., Ltd. (JP) | 2017-02-15 | — | — | EP | disclosed |
| WO-2015155976-A1 | (ANTI-HER2 ANTIBODY)-DRUG CONJUGATE | 第一三共株式会社 | 2015-10-15 | — | — | WO | disclosed |
| WO-1994013646-A1 | N,N-DIACYLPIPERAZINE TACHYKININ ANTAGONISTS | MERCK & CO., INC. (US) | 1994-06-23 | — | — | WO | disclosed |
| US-3931268-A | Methylhydrazinomethyl-substituted benzoic acid amides | HOFFMANN-LA ROCHE INC. (US) | 1976-01-06 | — | — | US | disclosed |