Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | TDO2 | P48775 | 3/20 | 0.37 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 3/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | CDC42 | P60953 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11540707 | 0.86 | DAO (0.39) | DAOMCL1KDM4EALDH1A1HPGD | |
| SCHEMBL11542571 | 0.84 | CNR1 (0.43) | IDO1TDO2MGAMGAASI | |
| SCHEMBL11539443 | 0.82 | ACP3 (0.41) | ACP3IDO1TDO2IDO2HSD17B2 | |
| SCHEMBL3159487 | 0.78 | DAO (0.38) | DAOROCK2CDC42ROCK1PKN2 | |
| 2-Chlorophenyl-Bisphenylmethane(Major) SCHEMBL41575 | 0.77 | IDO1 (0.55) | ACP3IDO1TDO2IDO2MGAM | |
| SCHEMBL11536497 | 0.76 | CYP19A1 (0.40) | DAOMCL1 | |
| 2-Chlorophenyl-Bisphenylmethane(Major) SCHEMBL29279416 | 0.75 | IDO1 (0.57) | ACP3IDO1TDO2IDO2KDM4E | |
| SCHEMBL11538049 | 0.74 | CNR1 (0.43) | ACP3IDO1TDO2HSD17B2DAO | |
| SCHEMBL11537810 | 0.72 | NR3C1 (0.44) | HSD17B2MGAMGAASIMGAM2 | |
| SCHEMBL11542166 | 0.70 | GAA (0.45) | DAOMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138488-A | Diphenylmethyl picolinic acid derivatives and their use as anti-acne agents | SCHERING CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |