Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | TTK | P33981 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11542571 | 0.91 | CNR1 (0.43) | MCL1 | |
| SCHEMBL11538049 | 0.87 | CNR1 (0.43) | DAOALDH1A1 | |
| SCHEMBL11538902 | 0.86 | ACP3 (0.39) | DAOMAPTKDM4EMCL1ALDH1A1 | |
| SCHEMBL11537810 | 0.84 | NR3C1 (0.44) | MAPTNR3C1PGRNR3C2AR | |
| SCHEMBL11542166 | 0.82 | GAA (0.45) | DAOMAPTTHRBMCL1ALDH1A1 | |
| SCHEMBL11536497 | 0.82 | CYP19A1 (0.40) | DAOMCL1 | |
| SCHEMBL11535398 | 0.82 | GAA (0.42) | DAOMAPTKDM4E | |
| SCHEMBL11537244 | 0.80 | BRD4 (0.43) | DAOMAPTAURKATHRBCASP1 | |
| SCHEMBL3159487 | 0.80 | DAO (0.38) | DAOMAPTAURKATHRBCASP1 | |
| SCHEMBL3175370 | 0.77 | NAPRT (0.42) | DAOMAPTAURKAAURKBINCENP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138488-A | Diphenylmethyl picolinic acid derivatives and their use as anti-acne agents | SCHERING CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |