Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | DAO | P14920 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11536497 | 0.83 | CYP19A1 (0.40) | DAOMCL1 | |
| SCHEMBL11535398 | 0.83 | GAA (0.42) | GAADAOMAPT | |
| SCHEMBL11540707 | 0.82 | DAO (0.39) | MEN1KMT2ADAOMAPTALDH1A1 | |
| SCHEMBL3175909 | 0.78 | MEN1 (0.46) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11537810 | 0.72 | NR3C1 (0.44) | GAAMAPTALDH1A1TDP1MGAM | |
| SCHEMBL11537244 | 0.70 | BRD4 (0.43) | MEN1KMT2ADAOMAPTALDH1A1 | |
| SCHEMBL11538902 | 0.70 | ACP3 (0.39) | GAAMEN1KMT2ADAOMAPT | |
| SCHEMBL122911 | 0.69 | ACHE (0.57) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL22185347 | 0.66 | FABP4 (0.41) | DAOMAPTALDH1A1HTTMCL1 | |
| SCHEMBL3159487 | 0.63 | DAO (0.38) | DAOMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138488-A | Diphenylmethyl picolinic acid derivatives and their use as anti-acne agents | SCHERING CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |