Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1971090 | 0.86 | KCNN4 (0.48) | KIF11CYP19A1KCNN4ALDH1A1TSHR | |
| SCHEMBL10299579 | 0.82 | KCNA5 (0.50) | CYP19A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5999709 | 0.81 | KIF11 (0.49) | KIF11NOTUMKCNN4ALDH1A1TSHR | |
| SCHEMBL29101427 | 0.75 | KIF11 (0.40) | KIF11CYP11B1CYP11B2NOTUMCYP1A2 | |
| SCHEMBL11152853 | 0.75 | ESR1 (0.54) | KIF11CYP19A1NOTUMALDH1A1TSHR | |
| SCHEMBL6814948 | 0.74 | ESR1 (0.59) | KIF11CYP3A4ALDH1A1TSHRSLC6A2 | |
| SCHEMBL19670976 | 0.74 | TAAR1 (0.50) | KIF11CYP11B1CYP11B2NOTUMCYP2C19 | |
| SCHEMBL69485 | 0.74 | ESR1 (0.59) | KIF11CYP3A4ALDH1A1TSHRSLC6A2 | |
| SCHEMBL4339462 | 0.74 | NOTUM (0.50) | KIF11CYP11B1CYP11B2CYP19A1NOTUM | |
| SCHEMBL370451 | 0.74 | MIF (0.53) | KIF11CYP11B1CYP11B2CYP19A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138488-A | Diphenylmethyl picolinic acid derivatives and their use as anti-acne agents | SCHERING CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |