Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | KIF11 | P52732 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.44 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503257 | 0.88 | MIF (0.65) | MIFCYP2C19HIF1AKIF11CYP1A2 | |
| SCHEMBL20546665 | 0.86 | MIF (0.63) | MIFCYP2C19HIF1AKIF11CYP1A2 | |
| SCHEMBL2291379 | 0.78 | MIF (0.60) | MIFCYP2C19HIF1AKIF11CYP3A4 | |
| SCHEMBL28132726 | 0.77 | CYP2C19 (0.41) | MIFCYP2C19HIF1AKIF11CYP1A2 | |
| SCHEMBL7887393 | 0.77 | CYP2C19 (0.60) | MIFCYP2C19HIF1AKIF11ALDH1A1 | |
| SCHEMBL11615834 | 0.77 | MIF (0.89) | MIFCYP2C19HIF1AKIF11CYP1A2 | |
| SCHEMBL5929601 | 0.74 | CYP2C19 (0.47) | MIFCYP2C19HIF1AKIF11CYP1A2 | |
| SCHEMBL9453195 | 0.74 | NAPRT (0.40) | MIFCYP2C19HIF1AKIF11CYP1A2 | |
| SCHEMBL5580424 | 0.74 | KIF11 (0.48) | CYP2C19HIF1AKIF11CYP1A2CYP3A4 | |
| SCHEMBL11539617 | 0.74 | KIF11 (0.46) | CYP2C19HIF1AKIF11CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |