Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | GAPDH | P04406 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 9/20 | 0.46 |
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11502646 | 0.78 | USP2 (0.67) | KMT2AGAPDHMAPTMEN1ALDH1A1 | |
| SCHEMBL11539898 | 0.75 | KMT2A (0.46) | KMT2AMAPTMEN1ALDH1A1HTT | |
| SCHEMBL11850800 | 0.72 | USP2 (0.60) | KMT2AGAPDHMAPTMEN1RAB9A | |
| SCHEMBL11470370 | 0.67 | USP2 (0.67) | KMT2AGAPDHMAPTMEN1ALDH1A1 | |
| SCHEMBL15427115 | 0.67 | MAPT (1.00) | KMT2AMAPTMEN1ALDH1A1HTT | |
| SCHEMBL1520029 | 0.67 | KMT2A (1.00) | KMT2AGAPDHMAPTMEN1ALDH1A1 | |
| SCHEMBL10387798 | 0.65 | RAB9A (0.51) | KMT2AGAPDHMAPTMEN1ALDH1A1 | |
| SCHEMBL11652839 | 0.63 | USP2 (0.62) | KMT2AMEN1RAB9ANPC1LMNA | |
| SCHEMBL30788250 | 0.63 | RAB9A (1.00) | KMT2AMAPTMEN1ALDH1A1RAB9A | |
| SCHEMBL8909101 | 0.62 | RAB9A (0.76) | KMT2AMAPTMEN1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4127585-A | Isoxazol amides of 4-hydroxy-6H-thieno[2,3-b]thiopyran-5-carboxylic acid-7,7-dioxide | WARNER-LAMBERT COMPANY (US) | 1978-11-28 | — | — | US | claimed |
| US-4154734-A | Amides of 4-hydroxy-6H-thieno[2,3-b]thiopyran-5-carboxylic acid-7,7-dioxide | WARNER-LAMBERT COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4134897-A | Amides of 4-hydroxy-6H-thieno[2,3-b]thiopyran-5-carboxylic acid-7,7-dioxide and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1979-01-16 | — | — | US | disclosed |
| US-4127585-A | Isoxazol amides of 4-hydroxy-6H-thieno[2,3-b]thiopyran-5-carboxylic acid-7,7-dioxide | WARNER-LAMBERT COMPANY (US) | 1978-11-28 | — | — | US | disclosed |
| US-4082757-A | Amides of 4-hydroxy-6H-thieno[2,3-b]thiopyran-5-carboxylic acid-7,7-dioxide | WARNER-LAMBERT COMPANY (US) | 1978-04-04 | — | — | US | disclosed |