SCHEMBL11539880

SCHEMBL11539880

O=[PH](c1ccccc1)c1ccccc1.[N-]=[N+]=CC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.46
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
ALDH1A1 P00352 7/20 0.35
PKM P14618 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HSD17B10 Q99714 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
HIF1A Q16665 1/20 0.33
HDAC3 O15379 1/20 0.32
TNKS O95271 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC1 Q13547 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC2 Q92769 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL28566524 0.78 NPSR1 (0.50) NPSR1CYP1A2CYP2C9CYP2C19ALDH1A1
Benzene SCHEMBL28469520 0.76 NPSR1 (0.45) NPSR1CYP1A2CYP2C9CYP2C19ALDH1A1
Bromobenzene SCHEMBL28462787 0.76 NPSR1 (0.48) NPSR1CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL4693241 0.74 CA1 (0.30)
SCHEMBL2866591 0.74 CA1 (0.30)
SCHEMBL43130 0.73
SCHEMBL13583073 0.73 ALDH1A1 (0.35) ALDH1A1HTT
SCHEMBL1667 0.73 ALDH1A1 (0.35) ALDH1A1HTT
SCHEMBL23071547 0.71 ALDH1A1 (0.30) ALDH1A1
Methyl Alcohol SCHEMBL28358130 0.71 CA2 (0.38) ALDH1A1PKMSMN1; SMN2HSD17B10L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4154722-A PHOTOSTABILITY CIBA-GEIGY CORPORATION (US) 1979-05-15 US disclosed