Benzene

Benzene

SCHEMBL28469520

C.[N-]=[N+]=CC(=O)O.c1ccccc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.45
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
ALDH1A1 P00352 7/20 0.34
MEN1 O00255 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
HIF1A Q16665 1/20 0.34
PKM P14618 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TSHR P16473 2/20 0.30
TP53 P04637 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30
EGLN3 Q9H6Z9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43130 0.91
Ethylene SCHEMBL2495312 0.85
Formaldehyde SCHEMBL5133811 0.85
Butane SCHEMBL11012887 0.78 FAAH (0.39) NPSR1CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL11539880 0.76 NPSR1 (0.46) NPSR1CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL31162570 0.72 NPSR1 (0.42) NPSR1CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL11041849 0.69
Serine SCHEMBL442652 0.68 SLC1A1 (0.41) CYP1A2KMT2A
SCHEMBL28904420 0.65
SCHEMBL43175 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111808003-A Preparation method of thioether 甘肃农业大学 2020-10-23 CN disclosed