Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14346586 | 0.95 | MAPT (0.56) | CYP1A2CYP2C9CYP2C19CYP3A4MAPT | |
| SCHEMBL7409066 | 0.88 | ALDH1A1 (0.53) | CYP1A2CYP2C9CYP2C19CYP3A4MAPT | |
| SCHEMBL1722192 | 0.83 | MEN1 (0.54) | CYP1A2CYP2C9CYP2C19CYP3A4MAPT | |
| SCHEMBL3162185 | 0.82 | L3MBTL1 (0.60) | CYP1A2CYP2C9CYP2C19CYP3A4MAPT | |
| SCHEMBL2302836 | 0.80 | KMT2A (0.50) | L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28932704 | 0.79 | HTT (0.68) | CYP1A2CYP2C9CYP2C19CYP3A4MAPT | |
| SCHEMBL11539882 | 0.79 | GAA (0.56) | CYP1A2CYP2C9CYP2C19CYP3A4MAPT | |
| SCHEMBL7003848 | 0.79 | LMNA (0.49) | CYP1A2CYP2C9CYP2C19CYP3A4MAPT | |
| SCHEMBL11539971 | 0.79 | SMN1; SMN2 (0.56) | CYP1A2CYP2C9CYP2C19CYP3A4MAPT | |
| SCHEMBL2300941 | 0.79 | ALDH1A1 (0.52) | CYP1A2CYP3A4MAPTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156011-A | TREATMENT OF CARDIOVASCULAR DISORDERS | SOCIETE ANONYME DITE: LABORATOIRE L. LAFON (FR) | 1979-05-22 | — | — | US | disclosed |