SCHEMBL11540465

SCHEMBL11540465

Cc1c(C)c(OCCO)c(OCCO)c(-c2c(C)c(Br)c(Br)c(Br)c2Br)c1C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11544795 0.83 GAA (0.32) GAAKMT2AHSD17B10
SCHEMBL11540679 0.72 KMT2A (0.38) GAAKMT2AHSD17B10
SCHEMBL10883935 0.69 ALDH1A1 (0.37) GAAKMT2AHSD17B10
Alcohol SCHEMBL11043389 0.68 ALDH1A1 (0.40) GAAKMT2AHSD17B10
SCHEMBL11544464 0.67 GAA (0.34) GAAKMT2AHSD17B10
SCHEMBL4458251 0.66 TSHR (0.33)
SCHEMBL3182203 0.63 KMT2A (0.53) GAAKMT2AHSD17B10
SCHEMBL20201350 0.62 KMT2A (0.50) GAAKMT2AHSD17B10
SCHEMBL11706751 0.62 KMT2A (0.39) GAAKMT2AHSD17B10
SCHEMBL10614991 0.62 ALDH1A1 (0.33) HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4170711-A FLAME RETARDANTS FOR POLYESTERS, POLYCARBONATES, AND POLYURETHANES GENERAL ELECTRIC COMPANY (US) 1979-10-09 US disclosed