SCHEMBL11544795

SCHEMBL11544795

Cc1c(C)c(C)c(-c2c(Br)c(Br)c(Br)c(OCCO)c2OCCO)c(Br)c1C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11540465 0.83 GAA (0.32) GAAKMT2AHSD17B10
SCHEMBL11540679 0.76 KMT2A (0.38) GAAKMT2AHSD17B10
SCHEMBL11801681 0.75 LMNA (0.30)
SCHEMBL10883935 0.73 ALDH1A1 (0.37) GAAKMT2AHSD17B10
Alcohol SCHEMBL11043389 0.72 ALDH1A1 (0.40) GAAKMT2AHSD17B10
SCHEMBL11544464 0.70 GAA (0.34) GAAKMT2AHSD17B10
SCHEMBL6462701 0.65 CA2 (0.34) GAAKMT2AHSD17B10
SCHEMBL12403124 0.63
SCHEMBL17936458 0.63
SCHEMBL3182203 0.63 KMT2A (0.53) GAAKMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4170711-A FLAME RETARDANTS FOR POLYESTERS, POLYCARBONATES, AND POLYURETHANES GENERAL ELECTRIC COMPANY (US) 1979-10-09 US disclosed
US-3989531-A POLYSTYRENE GENERAL ELECTRIC COMPANY (US) 1976-11-02 US disclosed