SCHEMBL4458251

SCHEMBL4458251

Cc1c(Br)c(Br)c(Br)c(Br)c1-c1c(C)c(Br)c(Br)c(Br)c1Br

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4458254 0.86 TSHR (0.30) TSHR
SCHEMBL12440900 0.85 LMNA (0.35) TSHRCA1CA2CA4CA7
SCHEMBL10977615 0.85 LMNA (0.35) TSHRCA1CA2CA4CA7
SCHEMBL655518 0.79 CA1 (0.33) CA1CA2CA4
SCHEMBL95102 0.79 LMNA (0.40) CA1CA2CA4
SCHEMBL10614991 0.77 ALDH1A1 (0.33) CA1CA2CA4
SCHEMBL5109593 0.75 LMNA (0.38) CA1CA2CA4
Bromide SCHEMBL518116 0.75 LMNA (0.38) CA1CA2CA4
SCHEMBL5070588 0.75 LMNA (0.32) CA1CA2CA4
Calcium SCHEMBL5082390 0.75 LMNA (0.38) CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605207-B2 Heat resistance; using with polystyrene fthermoplastic foams BROMINE COMPOUNDS LTD. (IL) 2009-10-20 US disclosed
US-20080281024-A1 Flame Retardant Bromobenzyl Systems BROMINE COMPOUNDS LTD. (IL) 2008-11-13 US disclosed
EP-1951798-A2 FLAME RETARDANT BROMOBENZYL SYSTEMS Bromine Compounds Ltd. (IL) 2008-08-06 EP disclosed
WO-2007057900-A2 FLAME RETARDANT BROMOBENZYL SYSTEMS BROMINE COMPOUNDS LTD. (IL) 2007-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080281024-A1 Flame Retardant Bromobenzyl Systems PBRM1, PFAS, BPTF TSHR 1876/4885CA1 4855/4885CA2 4768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.