Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | HTR1D | P28221 | 5/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | SNCA | P37840 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | ICMT | O60725 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | GOT1 | P17174 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL892709 | 0.84 | HTR1D (0.73) | HTR2CCYP2D6HTR1DHTR1AHTR1B | |
| SCHEMBL30532276 | 0.84 | HTR1D (0.52) | HTR1DHTR1AHTR1BMPOSNCA | |
| SCHEMBL17375886 | 0.84 | HTR1D (0.52) | HTR1DHTR1AHTR1BMPOSNCA | |
| Hydrochloric Acid SCHEMBL21546043 | 0.83 | HTR1D (0.71) | HTR2CCYP2D6HTR1DHTR1AHTR1B | |
| SCHEMBL8693061 | 0.82 | HPGD (0.64) | HTR1DMPOSLC6A4SNCAMEN1 | |
| SCHEMBL8007177 | 0.81 | MPO (0.69) | HTR2CHTR1DHTR1AHTR1BMPO | |
| SCHEMBL2056337 | 0.81 | HTR1D (0.51) | HTR1DHTR1AHTR1BSNCAMEN1 | |
| SCHEMBL25284973 | 0.81 | HTR1D (0.77) | HTR2CCYP2D6HTR1DHTR1AHTR1B | |
| SCHEMBL29282842 | 0.81 | MPO (0.49) | HTR1DHTR1AHTR1BMPOSLC6A4 | |
| SCHEMBL22879684 | 0.79 | HTR1D (0.50) | HTR1DHTR1AHTR1BSNCAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4406957-B1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | NOGRA PHARMA LTD (IE) | 2026-04-08 | — | — | EP | disclosed |
| US-12577256-B2 | Aryl receptor modulators and methods of making and using the same | NOGRA PHARMA LIMITED (IE) | 2026-03-17 | — | — | US | disclosed |
| US-20250066384-A1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | NOGRA PHARMA LIMITED (IE) | 2025-02-27 | — | — | US | disclosed |
| EP-4406957-A2 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | Nogra Pharma Limited (IE) | 2024-07-31 | — | — | EP | disclosed |
| US-12012418-B2 | Aryl receptor modulators and methods of making and using the same | NOGRA PHARMA LIMITED (IE) | 2024-06-18 | — | — | US | disclosed |
| EP-3160964-B1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | NOGRA PHARMA LTD (IE) | 2024-03-13 | — | — | EP | disclosed |
| CN-116947880-A | Aryl receptor modulators and methods of making and using the same | 诺格拉制药有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-111978319-B | Aryl receptor modulators and methods of making and using the same | 诺格拉制药有限公司 | 2023-08-11 | — | — | CN | disclosed |
| US-20230234963-A1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | NOGRA PHARMA LIMITED (IE) | 2023-07-27 | — | — | US | disclosed |
| US-20230234963-A1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | NOGRA PHARMA LIMITED (IE) | 2023-07-27 | — | — | US | disclosed |
| US-11427600-B2 | Aryl receptor modulators and methods of making and using the same | NOGRA PHARMA LIMITED (IE) | 2022-08-30 | — | — | US | disclosed |
| CN-111978319-A | Aryl receptor modulators and methods of making and using the same | 诺格拉制药有限公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-106536520-B | Aryl receptor modulators and methods of making and using the same | 诺格拉制药有限公司 | 2020-08-14 | — | — | CN | disclosed |
| US-20170158707-A1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | NOGRA PHARMA LIMITED (IE) | 2017-06-08 | — | — | US | disclosed |
| US-20170158707-A1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | NOGRA PHARMA LIMITED (IE) | 2017-06-08 | — | — | US | disclosed |
| EP-3160964-A1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | Nogra Pharma Limited (IE) | 2017-05-03 | — | — | EP | disclosed |
| CN-106536520-A | Aryl receptor modulators and methods of making and using the same | 诺格拉制药有限公司 | 2017-03-22 | — | — | CN | disclosed |
| WO-2015197861-A1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | NOGRA PHARMA LIMITED (IE) | 2015-12-30 | — | — | WO | disclosed |
| WO-2015197861-A1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | NOGRA PHARMA LIMITED (IE) | 2015-12-30 | — | — | WO | disclosed |
| US-4171443-A | 10B-Azafluoranthene derivatives and precursors thereof | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1979-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12577256-B2 | Aryl receptor modulators and methods of making and using the same | AHR, IL23R, ARNT | HTR2C 136/4885CYP2D6 280/4885HTR1D 942/4885 |
| US-20250066384-A1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | AHR, IFNAR1, IL23R | HTR2C 180/4885CYP2D6 103/4885HTR1D 949/4885 |
| US-12012418-B2 | Aryl receptor modulators and methods of making and using the same | AHR, IL23R, IL2RA | HTR2C 209/4885CYP2D6 134/4885HTR1D 722/4885 |
| US-20170158707-A1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | AHR, IL23R, IL2RA | HTR2C 209/4885CYP2D6 134/4885HTR1D 722/4885 |
| US-11427600-B2 | Aryl receptor modulators and methods of making and using the same | AHR, IL23R, IL2RA | HTR2C 209/4885CYP2D6 134/4885HTR1D 722/4885 |
| US-20230234963-A1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | AHR, IL23R, IL2RA | HTR2C 209/4885CYP2D6 134/4885HTR1D 722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.