Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11535928 | 0.67 | KMT2A (0.49) | LMNATDP1GAASMN1; SMN2CYP3A4 | |
| SCHEMBL36575 | 0.66 | — | — | |
| SCHEMBL11533405 | 0.66 | CYP19A1 (0.45) | LMNATDP1CYP3A4 | |
| Bromide SCHEMBL28096484 | 0.66 | LMNA (0.42) | LMNATDP1GAASMN1; SMN2CYP3A4 | |
| Bromide SCHEMBL28350490 | 0.65 | LMNA (0.48) | LMNATDP1GAASMN1; SMN2CYP3A4 | |
| Hydrochloric Acid SCHEMBL1007846 | 0.65 | — | — | |
| SCHEMBL19418810 | 0.64 | LMNA (0.37) | LMNATDP1GAASMN1; SMN2CYP3A4 | |
| Bromide SCHEMBL28285798 | 0.64 | LMNA (0.44) | LMNATDP1GAASMN1; SMN2CYP3A4 | |
| SCHEMBL14993981 | 0.63 | — | — | |
| SCHEMBL27858135 | 0.63 | LMNA (0.43) | LMNATDP1GAASMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444711-A | Double-function heterogeneous catalyst and preparation method and application thereof | 浙江理工大学嵊州创新研究院有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-116444711-A | Double-function heterogeneous catalyst and preparation method and application thereof | 浙江理工大学嵊州创新研究院有限公司 | 2023-07-18 | — | — | CN | disclosed |