Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 4/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 5/20 | 0.35 |
| ▸ | DRD2 | P14416 | 5/20 | 0.35 |
| ▸ | DRD1 | P21728 | 5/20 | 0.35 |
| ▸ | DRD4 | P21917 | 5/20 | 0.35 |
| ▸ | DRD5 | P21918 | 5/20 | 0.35 |
| ▸ | DRD3 | P35462 | 5/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11306972 | 1.00 | TLR2 (0.41) | TLR2PLA2G2AALDH1A1TDP1PLA2G10 | |
| SCHEMBL11301728 | 0.93 | PLA2G2A (0.44) | TLR2PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL11299159 | 0.78 | HTT (0.41) | TLR2PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL10604671 | 0.77 | PLA2G10 (0.47) | TLR2PLA2G2ATDP1PLA2G10PLA2G1B | |
| SCHEMBL10604578 | 0.77 | PLA2G10 (0.47) | TLR2PLA2G2ATDP1PLA2G10PLA2G1B | |
| SCHEMBL10605748 | 0.77 | PLA2G10 (0.47) | TLR2PLA2G2ATDP1PLA2G10PLA2G1B | |
| SCHEMBL18641859 | 0.77 | PLA2G10 (0.47) | TLR2PLA2G2ATDP1PLA2G10PLA2G1B | |
| SCHEMBL5271487 | 0.76 | SPHK2 (0.52) | DRD2 | |
| SCHEMBL11298010 | 0.75 | FFAR1 (0.41) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL6813695 | 0.74 | PLA2G10 (0.50) | TLR2PLA2G2ATDP1PLA2G10PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4173641-A | ANTITUMOR | PFIZER INC. (US) | 1979-11-06 | — | — | US | disclosed |