Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4720589 | 0.83 | HTT (0.36) | GBA1HTT | |
| SCHEMBL4723956 | 0.83 | TDP1 (0.37) | GBA1ALDH1A1HTT | |
| SCHEMBL4723666 | 0.80 | CRHR1 (0.42) | ALDH1A1HTT | |
| SCHEMBL15789297 | 0.80 | SLC29A1 (0.46) | HTT | |
| SCHEMBL18641556 | 0.77 | DNM1 (0.40) | ALDH1A1HTT | |
| SCHEMBL4723984 | 0.74 | MAPT (0.41) | HTT | |
| SCHEMBL3182836 | 0.71 | HTT (0.41) | ALDH1A1HTT | |
| SCHEMBL5824071 | 0.69 | DNM1 (0.39) | HTT | |
| SCHEMBL4765553 | 0.68 | SMN1; SMN2 (0.39) | HTT | |
| SCHEMBL7236348 | 0.68 | DNM1 (0.43) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167567-A | Antihypertensive 4-aminoquinolines | THE UPJOHN COMPANY (US) | 1979-09-11 | — | — | US | disclosed |