SCHEMBL7236348

SCHEMBL7236348

CCCCCCCCN(CCCCCCCC)c1ncncn1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.43
DNM2 P50570 4/20 0.39
HTT P42858 1/20 0.36
NCOA1 Q15788 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NCOA3 Q9Y6Q9 1/20 0.36
USP2 O75604 2/20 0.34
TSHR P16473 2/20 0.34
LMNA P02545 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
APAF1 O14727 1/20 0.33
NR1I2 O75469 1/20 0.33
HSP90AA1 P07900 1/20 0.33
IDE P14735 1/20 0.33
UBE2N P61088 1/20 0.33
KCNH2 Q12809 1/20 0.33
THRB P10828 1/20 0.32
CRHR1 P34998 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5824071 0.98 DNM1 (0.39) DNM1DNM2HTTNCOA1SMN1; SMN2
SCHEMBL18641556 0.92 DNM1 (0.40) DNM1DNM2HTTNCOA1SMN1; SMN2
SCHEMBL3182836 0.92 HTT (0.41) DNM1DNM2HTTNCOA1SMN1; SMN2
SCHEMBL4765553 0.88 SMN1; SMN2 (0.39) DNM2HTTNCOA1SMN1; SMN2NCOA3
SCHEMBL4723666 0.84 CRHR1 (0.42) DNM2HTTNCOA1SMN1; SMN2NCOA3
SCHEMBL28220432 0.83 DNM1 (0.46) DNM1DNM2HTTSMN1; SMN2USP2
SCHEMBL4723984 0.83 MAPT (0.41) HTTSMN1; SMN2HSP90AA1CRHR1
SCHEMBL28232057 0.81 DNM1 (0.42) DNM1DNM2HTTNCOA1SMN1; SMN2
SCHEMBL9325170 0.79 HTT (0.34) HTTNCOA1SMN1; SMN2NCOA3CRHR1
SCHEMBL8976864 0.78 DNM1 (0.32) DNM1DNM2TSHRCYP2D6KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108367467-A Plastic-metal joint portion and its manufacturing method SABIC环球技术有限责任公司 2018-08-03 CN disclosed
US-6630272-B1 Having stable, low resistance 6-dialkylamino-1,3,5-triazine-2,4-dithiol cathodic film; inhibiting deterioration from generated gas MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2003-10-07 US disclosed