Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28851168 | 0.81 | SIGMAR1 (0.61) | PLK1SIGMAR1GAAALDH1A1PGR | |
| SCHEMBL28068452 | 0.81 | SIGMAR1 (0.50) | PLK1SIGMAR1GAAALDH1A1MTNR1A | |
| SCHEMBL11360909 | 0.78 | SIGMAR1 (0.51) | PLK1SIGMAR1GAANR4A1NR4A2 | |
| SCHEMBL10492074 | 0.78 | SIGMAR1 (0.57) | PLK1SIGMAR1GAAALDH1A1PGR | |
| SCHEMBL11541431 | 0.77 | TP53 (0.39) | GAAALDH1A1SLC6A2SLC6A4KDM4E | |
| SCHEMBL5966385 | 0.77 | SIGMAR1 (0.46) | SIGMAR1GAAALDH1A1MTNR1AMMP9 | |
| SCHEMBL11131086 | 0.76 | SIGMAR1 (0.46) | PLK1SIGMAR1GAAALDH1A1PGR | |
| SCHEMBL11542282 | 0.76 | ALDH1A1 (0.38) | GAAALDH1A1HSD17B10SLC6A2SLC6A4 | |
| SCHEMBL11514484 | 0.75 | LMNA (0.35) | PLK1HDAC8 | |
| SCHEMBL11548288 | 0.75 | ALDH1A1 (0.39) | ALDH1A1PTGS1MAPK1HSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148799-A | Process for the preparation of 2-aryliminothiazoline solutions | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-10 | — | — | US | disclosed |