Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | AGER | Q15109 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | FDPS | P14324 | 2/20 | 0.47 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11538552 | 0.79 | APAF1 (0.55) | TDP1AGERMAPTMAPK1POLB | |
| SCHEMBL11535480 | 0.78 | APAF1 (0.54) | TDP1AGERMAPTMAPK1POLB | |
| SCHEMBL3002573 | 0.76 | TDP1 (0.68) | TDP1MAPK1TSHRFDPSGGPS1 | |
| SCHEMBL226221 | 0.73 | TDP1 (0.70) | TDP1MAPK1APAF1CYP11B1CYP11B2 | |
| SCHEMBL6176569 | 0.73 | APAF1 (0.68) | TDP1AGERMAPTMAPK1POLB | |
| SCHEMBL6175278 | 0.73 | APAF1 (0.68) | TDP1AGERMAPTMAPK1POLB | |
| SCHEMBL11536548 | 0.73 | TDP1 (0.54) | TDP1AGERMAPK1TSHRAPAF1 | |
| SCHEMBL6791275 | 0.73 | GGPS1 (0.64) | TDP1AGERMAPTMAPK1POLB | |
| SCHEMBL6174975 | 0.72 | TDP1 (0.68) | TDP1AGERMAPTMAPK1POLB | |
| SCHEMBL13545635 | 0.72 | APAF1 (0.61) | TDP1AGERMAPTMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177155-A | N-AMINOMETHYL-TRIAZOLES AND IMIDAZOLES FOR MAKING ANTIFREEZES NONCORROSIVE | CIBA-GEIGY CORPORATION (US) | 1979-12-04 | — | — | US | disclosed |