SCHEMBL226221

SCHEMBL226221

CCn1cnc2ccccc21

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.70
CYP11B1 P15538 7/20 0.61
CYP11B2 P19099 7/20 0.61
TNF P01375 1/20 0.61
HTT P42858 4/20 0.59
LMNA P02545 4/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
MAPK1 P28482 2/20 0.56
PKM P14618 1/20 0.56
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
EGLN3 Q9H6Z9 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
APAF1 O14727 1/20 0.54
ALDH1A1 P00352 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL230355 0.94 TDP1 (0.63) TDP1CYP11B1CYP11B2TNFHTT
SCHEMBL229631 0.93 TDP1 (0.61) TDP1CYP11B1CYP11B2TNFHTT
SCHEMBL2380384 0.91 TDP1 (0.65) TDP1CYP11B1CYP11B2TNFHTT
Benzimidazole SCHEMBL10434506 0.85 TDP1 (0.53) TDP1CYP11B1CYP11B2TNFHTT
SCHEMBL9450146 0.85 TDP1 (0.62) TDP1CYP11B1CYP11B2TNFHTT
SCHEMBL230330 0.84 TDP1 (0.78) TDP1CYP11B1CYP11B2TNFHTT
SCHEMBL6794361 0.83 TDP1 (0.76) TDP1CYP11B1CYP11B2TNFHTT
SCHEMBL6442808 0.83 TDP1 (1.00) TDP1CYP11B1CYP11B2TNFHTT
SCHEMBL30564238 0.83 TDP1 (0.76) TDP1CYP11B1CYP11B2TNFHTT
Bromide SCHEMBL10912945 0.82 TDP1 (0.75) TDP1CYP11B1CYP11B2TNFHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 457 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250361280-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS INC (US) 2025-11-27 US claimed
CN-116606290-B Method for efficiently catalyzing and synthesizing fluorine-containing polypeptide condensing agent by adopting green acid binding agent 浙江大学 2024-11-01 CN claimed
CN-115832607-B Preparation method of battery diaphragm, battery diaphragm and secondary battery 宁德时代新能源科技股份有限公司 2024-10-18 CN claimed
CN-116606290-A Method for efficiently catalyzing and synthesizing fluorine-containing polypeptide condensing agent by adopting green acid binding agent 浙江大学 2023-08-18 CN claimed
CN-115832607-A Preparation method of battery diaphragm, battery diaphragm and secondary battery 宁德时代新能源科技股份有限公司 2023-03-21 CN claimed
CN-107880079-B Cyclic N-heterocyclic bis-carbene-palladium complex and preparation method and application thereof 天津师范大学 2020-05-08 CN claimed
EP-1984968-B1 IONIC LIQUID ELECTROLYTE ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) 2017-04-05 EP claimed
EP-2419551-A2 ELECTROLYTE AND SURFACE-ACTIVE ADDITIVES FOR THE GALVANIC DEPOSITION OF SMOOTH, DENSE ALUMINUM LAYERS FROM IONIC LIQUIDS BASF SE (DE) 2012-02-22 EP claimed
US-20120006688-A1 ELECTROLYTE AND SURFACE-ACTIVE ADDITIVES FOR THE ELECTROCHEMICAL DEPOSITION OF SMOOTH, DENSE ALUMINUM LAYERS FROM IONIC LIQUIDS BASF SE (DE) 2012-01-12 US claimed
US-20120001134-A1 LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS PLEOTINT, LLC (US) 2012-01-05 US claimed
WO-2010106072-A2 ELECTROLYTE AND SURFACE-ACTIVE ADDITIVES FOR THE GALVANIC DEPOSITION OF SMOOTH, DENSE ALUMINUM LAYERS FROM IONIC LIQUIDS BASF SE (DE) 2010-09-23 WO claimed
US-20090283728-A1 LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS PLEOTINT, LLC (US) 2009-11-19 US claimed
EP-2082005-A1 LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS Pleotint, L.L.C. (US) 2009-07-29 EP claimed
US-20080100902-A1 LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS PLEOTINT, LLC (US) 2008-05-01 US claimed
WO-2008028128-A1 LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS PLEOTINT, L.L.C. (US) 2008-03-06 WO claimed
US-5441563-A Antifoam agents in printing inks ARMSTRONG WORLD INDUSTRIES, INC. (US) 1995-08-15 US claimed
EP-0271260-B1 Supersensitization of silver halide emulsions MINNESOTA MINING & MFG (US) 1995-01-04 EP claimed
US-4873184-A ADDITION OF A METAL COMPLEXING AGENT TO THE EMULSION; HIGH SPEED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-10 US claimed
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 EP claimed
US-4662905-A REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) 1987-05-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250361280-A1 CONJUGATED HEPCIDIN MIMETICS HAMP, VIP, HDGF TDP1 4878/4885CYP11B1 971/4885CYP11B2 968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.