Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549621 | 0.99 | SIGMAR1 (0.42) | LTA4HSIGMAR1GAASLC6A3DRD2 | |
| SCHEMBL11546820 | 0.99 | SIGMAR1 (0.42) | LTA4HSIGMAR1GAASLC6A3DRD2 | |
| SCHEMBL11546197 | 0.90 | SIGMAR1 (0.43) | SIGMAR1TMEM97 | |
| SCHEMBL11544153 | 0.81 | — | — | |
| SCHEMBL11545446 | 0.81 | SIGMAR1 (0.43) | LTA4HSIGMAR1SLC6A3TMEM97HRH3 | |
| SCHEMBL11544762 | 0.76 | SLC6A4 (0.34) | SLC6A3SLC6A4GRIN2B | |
| SCHEMBL11545456 | 0.76 | SLC6A2 (0.38) | SIGMAR1SLC6A3DRD2SLC6A4HRH3 | |
| SCHEMBL11544913 | 0.76 | MEN1 (0.39) | SIGMAR1GAASLC6A3DRD2SLC6A4 | |
| SCHEMBL11541733 | 0.75 | MEN1 (0.38) | SIGMAR1GAASLC6A3DRD2SLC6A4 | |
| SCHEMBL11543869 | 0.75 | SLC6A2 (0.38) | SIGMAR1SLC6A3DRD2SLC6A4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172093-A | Pharmacodynamically active indan derivatives | AB KABI (SE) | 1979-10-23 | — | — | US | disclosed |