Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | HRH1 | P35367 | 4/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | MC3R | P41968 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543869 | 0.99 | SLC6A2 (0.38) | SLC6A2SLC6A4HTR2AHRH1CHRM2 | |
| SCHEMBL11544443 | 0.91 | SLC6A2 (0.40) | SLC6A2SLC6A4HTR2AHRH1CHRM2 | |
| SCHEMBL11544153 | 0.82 | — | — | |
| SCHEMBL11544856 | 0.81 | SLC6A4 (0.38) | SLC6A2SLC6A4CHRM2CHRM1CHRM3 | |
| SCHEMBL11544139 | 0.81 | SLC6A4 (0.42) | SLC6A2SLC6A4HTR2AHRH1CHRM2 | |
| SCHEMBL11544913 | 0.80 | MEN1 (0.39) | SLC6A2SLC6A4HTR2AHRH1CHRM2 | |
| SCHEMBL11546166 | 0.80 | ALDH1A1 (0.35) | CHRM2CHRM1LMNACYP1A2CYP2D6 | |
| SCHEMBL11544136 | 0.79 | SLC6A4 (0.45) | SLC6A2SLC6A4HTR2AHRH1CHRM2 | |
| SCHEMBL11543451 | 0.79 | CHRM2 (0.35) | SLC6A2CHRM2CHRM1HRH3LMNA | |
| SCHEMBL11541733 | 0.79 | MEN1 (0.38) | SLC6A2SLC6A4HTR2AHRH1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172093-A | Pharmacodynamically active indan derivatives | AB KABI (SE) | 1979-10-23 | — | — | US | disclosed |