Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HRH1 | P35367 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11541733 | 0.99 | MEN1 (0.38) | MEN1KMT2ASLC6A2HTR2AHRH1 | |
| SCHEMBL11543909 | 0.91 | TAAR1 (0.37) | MEN1KMT2ASLC6A2HTR2AHRH1 | |
| SCHEMBL11544153 | 0.82 | — | — | |
| SCHEMBL11545456 | 0.80 | SLC6A2 (0.38) | MEN1KMT2ASLC6A2HTR2AHRH1 | |
| SCHEMBL11543869 | 0.79 | SLC6A2 (0.38) | MEN1KMT2ASLC6A2HTR2AHRH1 | |
| SCHEMBL11544762 | 0.77 | SLC6A4 (0.34) | MEN1KMT2ASLC6A2HTR2ASLC6A3 | |
| SCHEMBL11544443 | 0.77 | SLC6A2 (0.40) | MEN1KMT2ASLC6A2HTR2AHRH1 | |
| SCHEMBL11544108 | 0.76 | LTA4H (0.42) | SLC6A3DRD2GAASIGMAR1SLC6A4 | |
| SCHEMBL11546820 | 0.75 | SIGMAR1 (0.42) | HTR2ACYP2D6L3MBTL1SLC6A3KDM4E | |
| SCHEMBL11549621 | 0.75 | SIGMAR1 (0.42) | HTR2ACYP2D6L3MBTL1SLC6A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172093-A | Pharmacodynamically active indan derivatives | AB KABI (SE) | 1979-10-23 | — | — | US | claimed |
| US-4172093-A | Pharmacodynamically active indan derivatives | AB KABI (SE) | 1979-10-23 | — | — | US | disclosed |