Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.65 |
| ▸ | CASP6 | P55212 | 2/20 | 0.65 |
| ▸ | G6PD | P11413 | 1/20 | 0.65 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627392 | 0.81 | NSD2 (0.72) | NSD2CASP6G6PDMAOAMAOB | |
| SCHEMBL2268383 | 0.80 | NSD2 (0.70) | NSD2CASP6G6PDMAOAMAOB | |
| SCHEMBL423613 | 0.80 | CASP6 (0.70) | NSD2CASP6G6PDNPY1RKMT2A | |
| SCHEMBL12192928 | 0.79 | NSD2 (0.68) | NSD2CASP6G6PDNPY1RKMT2A | |
| SCHEMBL2274037 | 0.79 | NSD2 (1.00) | NSD2CASP6G6PDMAOAMAOB | |
| SCHEMBL2267864 | 0.79 | G6PD (1.00) | NSD2CASP6G6PDMAOAMAOB | |
| SCHEMBL11543737 | 0.77 | MAPT (0.47) | CASP6KMT2AHSP90AA1MEN1HSP90AB1 | |
| SCHEMBL4727380 | 0.77 | NSD2 (0.65) | NSD2CASP6G6PDMAOAMAOB | |
| SCHEMBL2273253 | 0.77 | NSD2 (0.65) | NSD2CASP6G6PDMAOAMAOB | |
| SCHEMBL10941471 | 0.75 | NSD2 (0.63) | NSD2CASP6G6PDMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167638-A | Process for production of 8-NHR quinolines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1979-09-11 | — | — | US | disclosed |