Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.47 |
| ▸ | MEN1 | O00255 | 8/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | CTSB | P07858 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | TDO2 | P48775 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1377784 | 0.83 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8901804 | 0.83 | MEN1 (0.54) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL10944706 | 0.82 | MAPT (0.59) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL5186834 | 0.82 | CASP6 (0.60) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL10945384 | 0.82 | G6PD (0.60) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL4728660 | 0.80 | ALDH1A1 (0.50) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL10943147 | 0.79 | CTSB (0.47) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2469901 | 0.78 | ALDH1A1 (0.61) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL11887409 | 0.77 | MAPT (0.64) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL11544229 | 0.77 | NSD2 (0.65) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167638-A | Process for production of 8-NHR quinolines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1979-09-11 | — | — | US | disclosed |