Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545236 | 0.90 | MAPKAPK2 (0.56) | MAPKAPK2MAPK1MAPTMEN1KMT2A | |
| SCHEMBL11543764 | 0.85 | MAPKAPK2 (0.53) | MAPKAPK2MAPK1MAPTMEN1KMT2A | |
| SCHEMBL11544277 | 0.85 | MAPKAPK2 (0.56) | MAPKAPK2MAPK1MAPTMEN1KMT2A | |
| SCHEMBL11542855 | 0.84 | MAPKAPK2 (0.54) | MAPKAPK2MAPK1MAPTMEN1KMT2A | |
| SCHEMBL11726280 | 0.84 | MAPKAPK2 (0.75) | MAPKAPK2MAPK1MAPTMEN1KMT2A | |
| SCHEMBL11542519 | 0.83 | MAPKAPK2 (0.54) | MAPKAPK2MAPK1MAPTMEN1KMT2A | |
| SCHEMBL11729429 | 0.82 | MAPKAPK2 (0.60) | MAPKAPK2MAPK1MAPTMEN1KMT2A | |
| SCHEMBL10838774 | 0.82 | MAPKAPK2 (0.61) | MAPKAPK2MAPK1MAPTMEN1KMT2A | |
| SCHEMBL11728397 | 0.81 | RAD52 (0.69) | MAPKAPK2MAPK1MAPTMEN1KMT2A | |
| SCHEMBL11522431 | 0.80 | MAPKAPK2 (0.51) | MAPKAPK2MAPK1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167567-A | Antihypertensive 4-aminoquinolines | THE UPJOHN COMPANY (US) | 1979-09-11 | — | — | US | disclosed |