Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544271 | 0.90 | MAPKAPK2 (0.56) | MAPKAPK2MAPTMEN1MAPK1STAT3 | |
| SCHEMBL11542120 | 0.87 | PRKAB2 (0.54) | MAPKAPK2MAPTKDM4ENPSR1PDGFRB | |
| SCHEMBL11544277 | 0.86 | MAPKAPK2 (0.56) | MAPKAPK2MAPTMEN1MAPK1STAT3 | |
| SCHEMBL11726280 | 0.84 | MAPKAPK2 (0.75) | MAPKAPK2MAPTMEN1MAPK1STAT3 | |
| SCHEMBL11542855 | 0.82 | MAPKAPK2 (0.54) | MAPKAPK2MAPTMEN1MAPK1STAT3 | |
| SCHEMBL11729429 | 0.82 | MAPKAPK2 (0.60) | MAPKAPK2MAPTMEN1MAPK1STAT3 | |
| SCHEMBL10838774 | 0.82 | MAPKAPK2 (0.61) | MAPKAPK2MAPTMEN1MAPK1STAT3 | |
| SCHEMBL11543764 | 0.82 | MAPKAPK2 (0.53) | MAPKAPK2MAPTMEN1MAPK1STAT3 | |
| SCHEMBL11724988 | 0.81 | MAPKAPK2 (0.56) | MAPKAPK2MAPTMEN1MAPK1STAT3 | |
| SCHEMBL11542519 | 0.81 | MAPKAPK2 (0.54) | MAPKAPK2MAPTMEN1MAPK1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167567-A | Antihypertensive 4-aminoquinolines | THE UPJOHN COMPANY (US) | 1979-09-11 | — | — | US | disclosed |