Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001513 | 0.98 | SIGMAR1 (0.45) | SIGMAR1RAD52POLBHRH3CXCR4 | |
| SCHEMBL13693501 | 0.94 | SIGMAR1 (0.39) | SIGMAR1RAD52HRH3CXCR4SMN1; SMN2 | |
| SCHEMBL11535998 | 0.91 | SIGMAR1 (0.45) | SIGMAR1RAD52POLBGLATDP1 | |
| SCHEMBL197822 | 0.86 | SIGMAR1 (0.55) | SIGMAR1RAD52POLBHRH3NAAA | |
| SCHEMBL30161367 | 0.85 | CXCR4 (0.43) | SIGMAR1HRH3CXCR4SMN1; SMN2NAAA | |
| SCHEMBL30969422 | 0.82 | CXCR4 (0.45) | HRH3CXCR4SMN1; SMN2NAAA | |
| SCHEMBL28348348 | 0.81 | SIGMAR1 (0.48) | SIGMAR1RAD52POLBHRH3NAAA | |
| SCHEMBL4573782 | 0.79 | HRH3 (0.47) | SIGMAR1RAD52HRH3NAAA | |
| SCHEMBL21184639 | 0.78 | SIGMAR1 (0.50) | SIGMAR1RAD52POLBHRH3NAAA | |
| SCHEMBL3990249 | 0.78 | GNAO1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4174428-A | CYCLIC TETRAAMINES WITH PENDANT AMINOALKYLS AND POLYSTYRENE WITH THE TETRAAMINE BONDED THERETO | Tabushi, Iwao (JP) | 1979-11-13 | — | — | US | disclosed |