SCHEMBL197822

SCHEMBL197822

NCCCCC1CCCNC1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.55
HRH3 Q9Y5N1 3/20 0.46
NAAA Q02083 1/20 0.43
HRH4 Q9H3N8 2/20 0.41
RAD52 P43351 1/20 0.41
KMT2A Q03164 2/20 0.41
POLB P06746 1/20 0.40
GLA P06280 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CPN1 P15169 1/20 0.37
CPB2 Q96IY4 1/20 0.37
ACP1 P24666 6/20 0.36
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA4 P43681 1/20 0.35
TLR7 Q9NYK1 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4573782 0.94 HRH3 (0.47) SIGMAR1HRH3NAAAHRH4RAD52
SCHEMBL21184639 0.88 SIGMAR1 (0.50) SIGMAR1HRH3NAAAHRH4RAD52
SCHEMBL28348348 0.88 SIGMAR1 (0.48) SIGMAR1HRH3NAAAHRH4RAD52
SCHEMBL11170648 0.87 HRH3 (0.51) SIGMAR1HRH3NAAAHRH4KMT2A
SCHEMBL11544455 0.86 SIGMAR1 (0.47) SIGMAR1HRH3NAAARAD52POLB
SCHEMBL1099712 0.85
SCHEMBL7704486 0.85 HRH3 (0.53) HRH3NAAAHRH4KMT2ACPN1
SCHEMBL9001513 0.84 SIGMAR1 (0.45) SIGMAR1HRH3NAAARAD52POLB
SCHEMBL5012792 0.81
SCHEMBL11535998 0.81 SIGMAR1 (0.45) SIGMAR1RAD52POLBGLATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2895517-B1 TWO-COMPONENT POLYURETHANE COMPOSITION SIKA TECH AG (CH) 2020-12-16 EP claimed
CN-104640894-B two-component polyurethane composition SIKA技术股份公司 2018-11-13 CN claimed
US-20150259465-A1 TWO-COMPONENT POLYURETHANE COMPOSITION SIKA TECHNOLOGY AG (CH) 2015-09-17 US claimed
EP-2895517-A1 TWO-COMPONENT POLYURETHANE COMPOSITION Sika Technology AG (CH) 2015-07-22 EP claimed
CN-104640894-A Two-component polyurethane composition SIKA TECHNOLOGY AG 2015-05-20 CN claimed
CN-101687775-B Aldimines and compositions comprising aldamine SIKA TECHNOLOGY AG 2015-05-06 CN claimed
CN-101765583-B Aldimines comprising hydroxyl groups, and compositions containing aldimine SIKA TECHNOLOGY AG 2014-06-04 CN claimed
CN-102224181-B Aldimine and composition containing aldimine SIKA TECHNOLOGY AG 2014-04-30 CN claimed
WO-2014040922-A1 TWO-COMPONENT POLYURETHANE COMPOSITION SIKA TECHNOLOGY AG (CH) 2014-03-20 WO claimed
EP-2706073-A1 Two-component polyurethane composition Sika Technology AG (CH) 2014-03-12 EP claimed
EP-1990387-A1 Composite layer body joined with polyurethane holt melt glue and method for gluing plastics containing dilutents Sika Technology AG (CH) 2008-11-12 EP claimed
EP-1979397-A2 SHAPE MEMORY CYANATE ESTER COPOLYMERS CORNERSTONE RESEARCH GROUP, INC. (US) 2008-10-15 EP claimed
EP-1975190-A1 Aldimines with reactive groups containing active hydrogen Sika Technology AG (CH) 2008-10-01 EP claimed
EP-1918314-A1 Polyurethane composition with high green strength Sika Technology AG (CH) 2008-05-07 EP claimed
WO-2008051241-A2 SHAPE MEMORY CYANATE ESTER COPOLYMERS CORNERSTONE RESEARCH GROUP, INC. (US) 2008-05-02 WO claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
EP-0424738-B1 Process for the preparation of amines BASF AG (DE) 1994-01-26 EP claimed
US-5132427-A Catalytic hydrogenation of 1,3,6-tricyanohexane using cobalt oxide containing catalyst BASF AKTIENGESELLSCHAFT (DE) 1992-07-21 US claimed
EP-0424738-A2 Process for the preparation of amines BASF Aktiengesellschaft (DE) 1991-05-02 EP claimed