Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 3/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.51 |
| ▸ | PRKAB2 | O43741 | 4/20 | 0.49 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.49 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.49 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.49 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.49 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.49 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543560 | 0.95 | KDM4E (0.58) | PDGFRBCNR1CNR2KDM4EMAPT | |
| SCHEMBL11545445 | 0.92 | PRKAB2 (0.56) | PDGFRBCNR1CNR2KDM4EMAPT | |
| SCHEMBL11541904 | 0.91 | PDGFRB (0.53) | PDGFRBCNR1CNR2KDM4EMAPT | |
| SCHEMBL11542120 | 0.91 | PRKAB2 (0.54) | PDGFRBCNR1CNR2KDM4EMAPT | |
| SCHEMBL11545275 | 0.91 | PRKAB2 (0.59) | PDGFRBCNR1CNR2KDM4EMAPT | |
| SCHEMBL28845655 | 0.90 | MAPKAPK2 (0.53) | PDGFRBMAPTNAMPTMAPKAPK2MEN1 | |
| SCHEMBL11542636 | 0.90 | PDGFRB (0.53) | PDGFRBCNR1CNR2KDM4EMAPT | |
| SCHEMBL11541414 | 0.88 | HTT (0.45) | PDGFRBKDM4EMAPTNPSR1MAPKAPK2 | |
| SCHEMBL11541218 | 0.87 | HPGDS (0.57) | PDGFRBCNR1CNR2KDM4EMAPT | |
| SCHEMBL11734243 | 0.87 | MAPKAPK2 (0.61) | NAMPTMAPKAPK2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167567-A | Antihypertensive 4-aminoquinolines | THE UPJOHN COMPANY (US) | 1979-09-11 | — | — | US | claimed |
| US-4167567-A | Antihypertensive 4-aminoquinolines | THE UPJOHN COMPANY (US) | 1979-09-11 | — | — | US | disclosed |