Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 2/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5511628 | 0.84 | ALDH1A1 (0.46) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL28055007 | 0.82 | ALDH1A1 (0.47) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL2986085 | 0.82 | ALDH1A1 (0.47) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL5515204 | 0.80 | KMT2A (0.47) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL11344529 | 0.77 | MAOB (0.41) | — | |
| SCHEMBL28564523 | 0.77 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL27749398 | 0.77 | CYP1A2 (0.48) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL28140482 | 0.76 | ALDH1A1 (0.52) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL11197533 | 0.76 | MAOA (0.40) | CYP1A2LMNAGAA | |
| SCHEMBL5348760 | 0.76 | ANPEP (0.43) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4164415-A | Branched alkyl-2-naphthaleneacetic acids as herbicides and insecticide intermediates | AMERICAN CYANAMID CO. (US) | 1979-08-14 | — | — | US | disclosed |
| US-4088782-A | Substituted-benzyl α-C1 -C4 alkyl-2-naphthaleneacetates as insecticidal agents | AMERICAN CYANAMID COMPANY (US) | 1978-05-09 | — | — | US | disclosed |
| US-4046799-A | INSECTICIDES | AMERICAN CYANAMID COMPANY (US) | 1977-09-06 | — | — | US | disclosed |