Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2986085 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL17782926 | 0.85 | ALDH1A1 (0.50) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL15641295 | 0.83 | AKR1B1 (0.51) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL28241058 | 0.83 | ALDH1A1 (0.48) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL15695555 | 0.83 | ALDH1A1 (0.48) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL448107 | 0.83 | AKR1B1 (0.51) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL8120419 | 0.83 | AKR1B1 (0.51) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL1566758 | 0.83 | ALDH1A1 (0.48) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL11544705 | 0.82 | ALDH1A1 (0.44) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL6897764 | 0.81 | ALDH1A1 (0.51) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109456201-B | Method for asymmetrically synthesizing (R) -cinacalcet | 中国农业大学 | 2020-04-28 | — | — | CN | claimed |
| CN-109456201-A | A kind of method of asymmetric syntheses (R)-cinacalcet | 中国农业大学 | 2019-03-12 | — | — | CN | claimed |
| CN-105510510-A | HPLC analytical method for chirality purity of 2-amino butanol | UNIV HEBEI SCIENCE & TECH | 2016-04-20 | — | — | CN | claimed |
| CN-105510263-A | HPLC analytical method for 3-amino piperidine isomer | UNIV HEBEI SCIENCE & TECH | 2016-04-20 | — | — | CN | claimed |
| CN-113341054-A | Method for measuring excess rate of 1-NEA enantiomer | 河北科技大学 | 2021-09-03 | — | — | CN | disclosed |
| CN-113341053-A | Analysis method for chiral purity of 1-naphthylethylamine | 河北科技大学 | 2021-09-03 | — | — | CN | disclosed |
| CN-109456201-B | Method for asymmetrically synthesizing (R) -cinacalcet | 中国农业大学 | 2020-04-28 | — | — | CN | disclosed |
| CN-109456201-B | Method for asymmetrically synthesizing (R) -cinacalcet | 中国农业大学 | 2020-04-28 | — | — | CN | disclosed |
| CN-109456201-A | A kind of method of asymmetric syntheses (R)-cinacalcet | 中国农业大学 | 2019-03-12 | — | — | CN | disclosed |
| CN-109456201-A | A kind of method of asymmetric syntheses (R)-cinacalcet | 中国农业大学 | 2019-03-12 | — | — | CN | disclosed |
| CN-105510510-B | HPLC analytical method for chirality purity of 2-amino butanol | 河北科技大学 | 2017-04-12 | — | — | CN | disclosed |
| CN-105675783-A | HPLC (high-performance liquid chromatography) analysis method of 3-aminobutanol chiral purity | 河北科技大学 | 2016-06-15 | — | — | CN | disclosed |
| CN-105510510-A | HPLC analytical method for chirality purity of 2-amino butanol | UNIV HEBEI SCIENCE & TECH | 2016-04-20 | — | — | CN | disclosed |
| CN-105510263-A | HPLC analytical method for 3-amino piperidine isomer | UNIV HEBEI SCIENCE & TECH | 2016-04-20 | — | — | CN | disclosed |