Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.40 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.35 |
| ▸ | RHEB | Q15382 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11458026 | 0.79 | GPR84 (0.44) | GPR84SLC6A2SLC6A3 | |
| SCHEMBL11542907 | 0.79 | HTT (0.55) | GPR84L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL28689451 | 0.79 | SOS1 (0.46) | GPR84TDO2L3MBTL1ALDH1A1HSPB1 | |
| SCHEMBL31220874 | 0.79 | SOS1 (0.46) | GPR84TDO2L3MBTL1ALDH1A1HSPB1 | |
| SCHEMBL7263349 | 0.77 | LTA4H (0.52) | GPR84L3MBTL1MEN1KMT2A | |
| SCHEMBL5593078 | 0.76 | SLC6A2 (0.42) | GPR84TDO2ALDH1A1SLC6A2SLC6A3 | |
| SCHEMBL702582 | 0.75 | PARP10 (0.58) | PARP10L3MBTL1CXCL8ALDH1A1ESR1 | |
| SCHEMBL31148976 | 0.73 | GPR84 (0.41) | GPR84 | |
| SCHEMBL22289312 | 0.73 | GPR84 (0.41) | GPR84 | |
| SCHEMBL31674528 | 0.73 | TDO2 (0.40) | GPR84TDO2L3MBTL1ALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179563-A | COGNITION ACTIVATORS | WARNER-LAMBERT COMPANY (US) | 1979-12-18 | — | — | US | disclosed |