Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543907 | 0.81 | SLC6A4 (0.38) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL11544440 | 0.81 | SLC6A3 (0.38) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL11503128 | 0.80 | SLC6A2 (0.31) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL11294673 | 0.78 | SLC6A4 (0.34) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL11544999 | 0.78 | AKR1C1 (0.37) | — | |
| SCHEMBL11545389 | 0.77 | SLC6A4 (0.36) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL11544250 | 0.77 | TAAR1 (0.39) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL11553286 | 0.77 | HDAC4 (0.31) | — | |
| SCHEMBL11295572 | 0.76 | LMNA (0.37) | — | |
| SCHEMBL11290081 | 0.76 | IDO1 (0.32) | SLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172093-A | Pharmacodynamically active indan derivatives | AB KABI (SE) | 1979-10-23 | — | — | US | claimed |
| US-4172093-A | Pharmacodynamically active indan derivatives | AB KABI (SE) | 1979-10-23 | — | — | US | disclosed |