Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544440 | 0.81 | SLC6A3 (0.38) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11544250 | 0.80 | TAAR1 (0.39) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11545483 | 0.78 | SLC6A2 (0.33) | SLC6A4SLC6A2SLC6A3HRH3HTR2A | |
| SCHEMBL11544758 | 0.77 | SLC6A3 (0.42) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11548561 | 0.77 | SLC6A4 (0.35) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL11291996 | 0.76 | SLC6A3 (0.33) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11542300 | 0.75 | HRH3 (0.33) | SLC6A4SLC6A3HRH3 | |
| SCHEMBL11543907 | 0.75 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11295572 | 0.74 | LMNA (0.37) | — | |
| SCHEMBL11544999 | 0.72 | AKR1C1 (0.37) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172093-A | Pharmacodynamically active indan derivatives | AB KABI (SE) | 1979-10-23 | — | — | US | claimed |