Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TST | Q16762 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437757 | 0.93 | ESR1 (0.50) | ESR1SLC6A2ADRA2AKDM4EALDH1A1 | |
| Butane SCHEMBL248656 | 0.84 | TDP1 (0.42) | ESR1ALDH1A1ESR2TDP1NPC1 | |
| Butane SCHEMBL8002745 | 0.84 | IDO1 (0.42) | ESR1SLC6A2ADRA2AKDM4EALDH1A1 | |
| Biphenyl SCHEMBL11546378 | 0.83 | ESR1 (0.46) | ESR1SLC6A2ADRA2AKDM4EALDH1A1 | |
| Butane SCHEMBL8387926 | 0.81 | THRB (0.39) | ALDH1A1LMNAL3MBTL1TDP1KMT2A | |
| SCHEMBL13284437 | 0.80 | CYP1A2 (0.47) | TAAR1L3MBTL1TDP1KMT2ANPC1 | |
| SCHEMBL437758 | 0.80 | ESR1 (0.52) | ESR1SLC6A2ADRA2AKDM4EALDH1A1 | |
| SCHEMBL22973728 | 0.77 | CES2 (0.36) | ALDH1A1CYP3A4HIF1ANPC1RAB9A | |
| SCHEMBL27190586 | 0.77 | TAAR1 (0.47) | KDM4ETAAR1L3MBTL1KMT2A | |
| SCHEMBL2817046 | 0.76 | TDP1 (0.47) | ESR1ALDH1A1SLC6A3LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168365-A | Flame-retardant phenolic resin | MATSUSHITA ELECTRIC WORKS, LTD. (JP) | 1979-09-18 | — | — | US | claimed |
| US-4168365-A | Flame-retardant phenolic resin | MATSUSHITA ELECTRIC WORKS, LTD. (JP) | 1979-09-18 | — | — | US | disclosed |