Biphenyl

Biphenyl

SCHEMBL11546378

O=[PH](O)OCCc1ccc(O)cc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.46
ESR2 Q92731 2/20 0.46
IDO1 P14902 1/20 0.45
MMP3 P08254 1/20 0.44
BCL2L1 Q07817 1/20 0.44
FFAR1 O14842 2/20 0.42
AKR1B10 O60218 1/20 0.41
AKR1B1 P15121 1/20 0.41
MAOB P27338 1/20 0.41
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HTR1A P08908 1/20 0.40
ADRA2A P08913 1/20 0.40
SLC6A2 P23975 1/20 0.40
CYP2C19 P33261 1/20 0.40
HTR3A P46098 1/20 0.40
BACE1 P56817 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL437757 0.90 ESR1 (0.50) ESR1ESR2IDO1KDM4EALDH1A1
SCHEMBL2817046 0.84 TDP1 (0.47) ESR1ESR2IDO1FFAR1AKR1B10
Butane SCHEMBL11544800 0.83 ESR1 (0.46) ESR1ESR2KDM4EALDH1A1HTR1A
Butane SCHEMBL248656 0.78 TDP1 (0.42) ESR1ESR2FFAR1ALDH1A1HCAR2
SCHEMBL437758 0.77 ESR1 (0.52) ESR1ESR2IDO1KDM4EALDH1A1
SCHEMBL17061044 0.74 LMNA (0.53) IDO1FFAR1MAOBALDH1A1TDP1
SCHEMBL27190586 0.74 TAAR1 (0.47) IDO1FFAR1MAOBKDM4ETAAR1
SCHEMBL13284437 0.74 CYP1A2 (0.47) IDO1FFAR1TAAR1L3MBTL1KMT2A
SCHEMBL22973728 0.74 CES2 (0.36) FFAR1ALDH1A1
SCHEMBL7301887 0.74 PLAU (0.49) FFAR1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4168365-A Flame-retardant phenolic resin MATSUSHITA ELECTRIC WORKS, LTD. (JP) 1979-09-18 US claimed
US-4168365-A Flame-retardant phenolic resin MATSUSHITA ELECTRIC WORKS, LTD. (JP) 1979-09-18 US disclosed