Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 4/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | TACR2 | P21452 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27660972 | 0.85 | TSHR (0.50) | TSHRKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL27660879 | 0.84 | TSHR (0.48) | TSHRADRA2AKDM4EALDH1A1LMNA | |
| SCHEMBL27680889 | 0.84 | TSHR (0.48) | TSHRKDM4EALDH1A1NPC1MAPT | |
| SCHEMBL248657 | 0.83 | TSHR (0.52) | TSHRACHEMAPTPOLBCA1 | |
| SCHEMBL282093 | 0.81 | PPARD (0.47) | TSHRESR1ESR2ADRA2AADORA3 | |
| SCHEMBL10636596 | 0.81 | MEN1 (0.50) | TSHRESR1ESR2ALDH1A1LMNA | |
| SCHEMBL27670172 | 0.81 | CYP4A11 (0.50) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL1421066 | 0.80 | TSHR (0.44) | TSHRKDM4EALDH1A1LMNATP53 | |
| SCHEMBL11126530 | 0.78 | CA1 (0.43) | TSHRCA1CA9CA2 | |
| SCHEMBL283016 | 0.78 | EGFR (0.47) | TSHRESR1ESR2ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168365-A | Flame-retardant phenolic resin | MATSUSHITA ELECTRIC WORKS, LTD. (JP) | 1979-09-18 | — | — | US | claimed |
| US-4168365-A | Flame-retardant phenolic resin | MATSUSHITA ELECTRIC WORKS, LTD. (JP) | 1979-09-18 | — | — | US | disclosed |