Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11126530 | 0.95 | CA1 (0.43) | TSHRNPSR1CA1CA2CA9 | |
| SCHEMBL27660972 | 0.85 | TSHR (0.50) | TSHRMAPTKCNH2POLB | |
| SCHEMBL27660879 | 0.83 | TSHR (0.48) | TSHR | |
| SCHEMBL27680889 | 0.83 | TSHR (0.48) | TSHRMAPTPOLBMEN1KMT2A | |
| SCHEMBL11544804 | 0.83 | TSHR (0.48) | TSHRMAPTPOLBACHECA1 | |
| SCHEMBL27670150 | 0.83 | TSHR (0.44) | TSHRMAPT | |
| SCHEMBL28878286 | 0.82 | TSHR (0.48) | TSHRNPSR1KCNH2POLBACHE | |
| SCHEMBL1238316 | 0.82 | TSHR (0.56) | TSHRNPSR1KCNH2POLBACHE | |
| SCHEMBL28761877 | 0.82 | TAAR1 (0.43) | TSHRMEN1KMT2A | |
| SCHEMBL5248630 | 0.80 | CETP (0.47) | TSHRNPSR1KCNH2POLBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110467795-B | Low-viscosity liquid oxygen compatible epoxy resin system for wet-process fiber winding and preparation method thereof | 大连理工大学 | 2021-02-23 | — | — | CN | claimed |
| EP-2545583-B1 | METHODS AND COMPOSITIONS FOR DOPING SILICON SUBSTRATES WITH MOLECULAR MONOLAYERS | VERSUM MAT US LLC (US) | 2020-05-13 | — | — | EP | claimed |
| US-9187621-B2 | Reflector for light-emitting devices | TICONA LLC (US) | 2015-11-17 | — | — | US | claimed |
| US-8906774-B2 | Methods and compositions for doping silicon substrates with molecular monolayers | DYNALOY, LLC (US) | 2014-12-09 | — | — | US | claimed |
| US-20140299907-A1 | Reflector for Light-Emitting Devices | TICONA LLC (US) | 2014-10-09 | — | — | US | claimed |
| EP-2545583-A1 | METHODS AND COMPOSITIONS FOR DOPING SILICON SUBSTRATES WITH MOLECULAR MONOLAYERS | Dynaloy, LLC (US) | 2013-01-16 | — | — | EP | claimed |
| US-20120003826-A1 | METHODS AND COMPOSITIONS FOR DOPING SILICON SUBSTRATES WITH MOLECULAR MONOLAYERS | VERSUM MATERIALS US, LLC | 2012-01-05 | — | — | US | claimed |
| WO-2011112546-A1 | METHODS AND COMPOSITIONS FOR DOPING SILICON SUBSTRATES WITH MOLECULAR MONOLAYERS | DYNALOY, LLC (US) | 2011-09-15 | — | — | WO | claimed |
| EP-2545583-B1 | METHODS AND COMPOSITIONS FOR DOPING SILICON SUBSTRATES WITH MOLECULAR MONOLAYERS | VERSUM MAT US LLC (US) | 2020-05-13 | — | — | EP | disclosed |
| US-9567460-B2 | Molded reflectors for light-emitting diode assemblies | TICONA LLC (US) | 2017-02-14 | — | — | US | disclosed |
| US-9453119-B2 | Polymer composition for producing articles with light reflective properties | TICONA LLC (US) | 2016-09-27 | — | — | US | disclosed |
| US-9187621-B2 | Reflector for light-emitting devices | TICONA LLC (US) | 2015-11-17 | — | — | US | disclosed |
| US-8906774-B2 | Methods and compositions for doping silicon substrates with molecular monolayers | DYNALOY, LLC (US) | 2014-12-09 | — | — | US | disclosed |
| EP-2797996-A1 | REFLECTOR FOR LIGHT-EMITTING DEVICES | Ticona LLC (US) | 2014-11-05 | — | — | EP | disclosed |
| EP-1730116-B1 | 4-CARBOX PYRAZOLE DERIVATES USEFUL AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORP (US) | 2007-09-05 | — | — | EP | disclosed |
| US-20070167507-A1 | 4-Carbox pyrazole derivatives useful as anti-viral agents | GLAXO GROUP LIMITED (GB) | 2007-07-19 | — | — | US | disclosed |
| CN-1989128-A | New 4-benzylidene-piperidin derivatives | RICHTER GEDEON VEGYESZET (HU) | 2007-06-27 | — | — | CN | disclosed |
| CN-1989126-A | Novel heterocyclic carboxylic acid amide derivatives | RICHTER GEDEON VEGYESZET (HU) | 2007-06-27 | — | — | CN | disclosed |
| EP-1730116-A1 | 4-CARBOX PYRAZOLE DERIVATES USEFUL AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005092863-A1 | 4-CARBOX PYRAZOLE DERIVATES USEFUL AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167507-A1 | 4-Carbox pyrazole derivatives useful as anti-viral agents | HAVCR2, RPL35, ZC3HAV1L | TSHR 3873/4885NPSR1 3202/4885MAPT 4522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.