Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544804 | 0.85 | TSHR (0.48) | TSHRKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL27680889 | 0.85 | TSHR (0.48) | TSHRCYP1A2TAAR1KDM4EALDH1A1 | |
| SCHEMBL27660879 | 0.85 | TSHR (0.48) | TSHRTAAR1KDM4EALDH1A1 | |
| SCHEMBL248657 | 0.85 | TSHR (0.52) | TSHRKCNH2MAPTPOLB | |
| SCHEMBL3196647 | 0.83 | TSHR (0.54) | TSHRKDM4EALDH1A1MAPT | |
| SCHEMBL10636596 | 0.82 | MEN1 (0.50) | TSHRKCNH2CYP1A2ALDH1A1MAPT | |
| SCHEMBL27670150 | 0.81 | TSHR (0.44) | TSHRTAAR1MAPT | |
| SCHEMBL1421066 | 0.81 | TSHR (0.44) | TSHRKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL17754402 | 0.81 | PPARD (0.44) | TSHRKCNH2CYP1A2CYP2A6TAAR1 | |
| SCHEMBL27670172 | 0.79 | CYP4A11 (0.50) | TSHRCYP1A2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1989126-A | Novel heterocyclic carboxylic acid amide derivatives | RICHTER GEDEON VEGYESZET (HU) | 2007-06-27 | — | — | CN | disclosed |