Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.36 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.36 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.36 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27660972 | 0.85 | TSHR (0.50) | TSHRKDM4EPOLBALDH1A1TAAR1 | |
| SCHEMBL27660879 | 0.84 | TSHR (0.48) | TSHRKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL11544804 | 0.84 | TSHR (0.48) | TSHRKDM4EPOLBALDH1A1NPC1 | |
| SCHEMBL248657 | 0.83 | TSHR (0.52) | TSHRPOLBMEN1KMT2AMAPT | |
| SCHEMBL10912425 | 0.81 | TAAR1 (0.44) | TSHRKDM4EPOLBALDH1A1GAA | |
| SCHEMBL1421066 | 0.80 | TSHR (0.44) | TSHRKDM4EPOLBALDH1A1L3MBTL1 | |
| SCHEMBL1833138 | 0.79 | FDPS (0.43) | KDM4EPOLBALDH1A1GAACTDSP1 | |
| SCHEMBL10636596 | 0.78 | MEN1 (0.50) | TSHRPOLBALDH1A1GAATDP1 | |
| SCHEMBL27670172 | 0.78 | CYP4A11 (0.50) | TSHRALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL917064 | 0.78 | NPY5R (0.42) | TSHRKDM4EPOLBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1989126-A | Novel heterocyclic carboxylic acid amide derivatives | RICHTER GEDEON VEGYESZET (HU) | 2007-06-27 | — | — | CN | disclosed |