Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549475 | 0.92 | TAAR1 (0.38) | SLC6A4MPOSRCSLC6A3CHRM2 | |
| SCHEMBL11544139 | 0.85 | SLC6A4 (0.42) | SLC6A4SLC6A3CHRM2CHRM4CHRM5 | |
| SCHEMBL11546149 | 0.82 | SLC6A4 (0.40) | SLC6A4SRCCHRM2CHRM4CHRM5 | |
| SCHEMBL11545456 | 0.81 | SLC6A2 (0.38) | SLC6A4SRCSLC6A3CHRM2CHRM4 | |
| SCHEMBL11543869 | 0.80 | SLC6A2 (0.38) | SLC6A4SLC6A3CHRM2CHRM4CHRM5 | |
| SCHEMBL11545626 | 0.79 | TAAR1 (0.38) | SLC6A4MPOSLC6A3SLC6A2TAAR1 | |
| SCHEMBL11544443 | 0.72 | SLC6A2 (0.40) | SLC6A4SLC6A3CHRM2CHRM4CHRM5 | |
| SCHEMBL11549473 | 0.69 | POLB (0.34) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL11638020 | 0.65 | TERT (0.45) | SLC6A4MPOSLC6A3 | |
| SCHEMBL8430524 | 0.65 | PGR (0.34) | MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172093-A | Pharmacodynamically active indan derivatives | AB KABI (SE) | 1979-10-23 | — | — | US | claimed |
| US-4172093-A | Pharmacodynamically active indan derivatives | AB KABI (SE) | 1979-10-23 | — | — | US | disclosed |