Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547227 | 0.86 | HPGD (0.47) | ALDH1A1NPC1RAB9ALMNAMEN1 | |
| SCHEMBL11545570 | 0.80 | HPGD (0.43) | ALDH1A1NPC1RAB9ALMNAMEN1 | |
| SCHEMBL11546116 | 0.76 | MEN1 (0.39) | ALDH1A1DPP4MEN1KMT2AKDM4E | |
| SCHEMBL10903756 | 0.75 | DPP4 (0.47) | ALDH1A1NPC1RAB9ADPP4MAPT | |
| SCHEMBL542283 | 0.74 | NOS2 (0.39) | DPP4 | |
| SCHEMBL7376051 | 0.74 | PRCP (0.34) | DPP4MEN1KMT2A | |
| SCHEMBL11164963 | 0.73 | CTNNB1 (0.47) | ALDH1A1MTNR1AMTNR1BLMNAMEN1 | |
| SCHEMBL7073415 | 0.73 | MTNR1A (0.62) | ALDH1A1MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL11544261 | 0.73 | ELANE (0.38) | ALDH1A1RAB9ADPP4 | |
| SCHEMBL7379917 | 0.72 | KMT2A (0.42) | DPP4KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154840-A | Antihypertensive pipecolic acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4105776-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS, HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1978-08-08 | — | — | US | disclosed |