Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.42 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.42 |
| ▸ | DHPS | P49366 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547272 | 0.82 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1HTTKMT2ATTBK1 | |
| SCHEMBL5316194 | 0.82 | SLC6A2 (0.47) | ALDH1A1MAPK1MEN1KMT2APOLB | |
| SCHEMBL5318993 | 0.81 | ACHE (0.50) | L3MBTL1ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL11547858 | 0.79 | KCNQ3 (0.48) | ALDH1A1PIN1MEN1KMT2AKCNQ3 | |
| SCHEMBL29417993 | 0.77 | — | — | |
| SCHEMBL942143 | 0.77 | — | — | |
| SCHEMBL3627857 | 0.77 | HTT (1.00) | L3MBTL1ALDH1A1MAPK1HTTCA12 | |
| SCHEMBL6630091 | 0.76 | CTNNB1 (0.59) | L3MBTL1HTTMEN1KMT2AKCNQ3 | |
| SCHEMBL11544017 | 0.76 | KCNQ3 (0.56) | MEN1KMT2AKCNQ3KCNQ2KCNE1 | |
| SCHEMBL4314680 | 0.76 | HTT (0.79) | L3MBTL1ALDH1A1MAPK1HTTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179506-A | TREATMENT OF SENILITY, REVERSAL OF AMNESIA | WARNER-LAMBERT COMPANY (US) | 1979-12-18 | — | — | US | disclosed |