Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316194 | 0.86 | SLC6A2 (0.47) | MAPTPOLBMEN1ALDH1A1KMT2A | |
| SCHEMBL5317845 | 0.82 | AR (0.44) | ALDH1A1ARSLC6A4SMN1; SMN2MPO | |
| SCHEMBL11544969 | 0.81 | L3MBTL1 (0.60) | L3MBTL1POLBMEN1ALDH1A1KMT2A | |
| SCHEMBL17258622 | 0.78 | ACHE (0.68) | ACHEMAPTL3MBTL1HPGDPOLB | |
| SCHEMBL17930598 | 0.77 | NPSR1 (0.49) | MAPTHPGDPOLBMEN1ALDH1A1 | |
| SCHEMBL15452397 | 0.77 | NPC1 (0.73) | ACHEMAPTL3MBTL1HPGDPOLB | |
| SCHEMBL15832088 | 0.76 | KCNQ3 (0.45) | MAPTL3MBTL1POLBSLC6A4RAB9A | |
| SCHEMBL20172428 | 0.75 | MPO (0.46) | MAPTL3MBTL1HPGDPOLBCYP2C9 | |
| SCHEMBL3893882 | 0.74 | PDGFRA (0.68) | — | |
| SCHEMBL31553439 | 0.74 | PDGFRA (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079173-A2 | NOVEL 2-HETEROARYLOXY-PHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS | EMERGENT BIOSOLUTIONS INC. (US) | 2007-07-12 | — | — | WO | disclosed |